S ynthetic dyes are used highly in many industries such as textile, paper-making, printing and dye manufacturing. The dye effluents of these industries are extremely colored and the discard of these toxic wastes into collected waters can affect the environment. Mostly, dyes are considerably toxic in nature and their presence in effluents may cause serious issues due to their potential negative effect on the aquatic life as well as human life. Moreover, dyes generally have complex aromatic structures and most of them are very difficult to degrade by physical, chemical and biological treatments. Many technologies are used such as adsorption, ultrasonic degradation, catalytic oxidation, photo catalytic degradation and microwave (MW)-enhanced advanced oxidation processes. Recently, MW-induced catalytic degradation has become a very promising technology in chemical applications due to its superior activity, short reaction time and especially when coupled with suitable MW absorbent. MW absorbing material spinel nickel ferrite, which used to degrade organic dyes under MW irradiation, was prepared by co-precipitation method of the mixed solution of ferric nitrate and nickel sulphate. The catalyst was characterized by field emission scanning electron microscopy-energy dispersive X-ray analysis (FESEM-EDX), nanoparticle tracking analysis (NTA), X-ray diffraction (XRD), UV-vis diffuse reflectance spectroscopy (DRS), thermal gravimetric analysis (TGA) and Fourier transform infrared spectroscopy (FTIR) to study the morphology and structural properties. NiFe2 O4 exhibits high catalytic activity for organic dyes such as Congo Red. The influence of catalyst dosage, initial dye concentration for dye degradation were also investigated. This work showed a high potential of NiFe2 O4 nanoparticles for environmental purification of organic pollutants.