Title : Boron nitride nano materials based heterogeneous catalyst as an efficient and highly biological active synthesis of methyl piperazinyl-quinolinyl fused Benzo(c)acridinone derivatives
Abstract:
Boron nitride nano material based solid acid catalyst was found to be an efficient and reusable sulfonic acid catalyst for the synthesis of one-pot Knoevenagel and Michael type reactions in 3, 3-dimethyl-9-(2-(4-methylpiperazin1-yl) quinolin-3-yl)-3, 4, 9, 10-tetrahydroacridin-1(2H)-one derivatives under microwave irradiation conditions. The synthesised catalyst was employed in Knoevenagel and Michael type reactions to synthesise novel piperazinylquinolinyl based acridine derivatives. Most importantly it was found that the solid acid catalyst can be recycled with only 5% loss of activity.